Estradiol vaginal inserts
Goodbye, dryness! Estradiol vaginal inserts restore moisture and ease irritation, so intimacy, bladder problems, and daily life feel more comfortable again.
Applies directly for fast, soothing, localized relief
Low-dose, localized hormone therapy
Just $49 per month with your membership
Speak with a doctor and unlock exclusive pricing with a Menopause Hormone Therapy Membership
Get your first month free!*
*A QuickMD doctor can prescribe medication only after your visit, and prescriptions aren’t guaranteed. The listed price covers medication only and doesn’t include the membership fee. Your MHT Membership gives you access to your doctor visit, ongoing support, and related care services. The first month is free, then renews at $79/month. You can cancel anytime.
Start hormone therapy
Perimenopause and menopause symptom relief. No insurance required.
Medication price for members:
Unlock exclusive pricing on medications when prescribed and filled through QuickMD by booking a visit to start your Menopause Hormone Therapy Membership.
Membership includes:
Same-day visits with an actual doctor
Get medications delivered directly to you
Get fast answers from our care team
Getting started with Estradiol vaginal inserts at QuickMD
Description
Estradiol vaginal inserts are a prescription medication that work locally to restore estrogen in the vaginal tissues. By delivering estrogen directly where it’s needed, they help relieve dryness, itching, burning, and discomfort during intimacy, while also supporting urinary health and lowering the risk of recurrent UTIs. Because inserts are low-dose and localized, very little is absorbed into the rest of the body, which helps minimize side effects. Estradiol vaginal inserts may also be prescribed for women who do not produce enough estrogen naturally. You can meet with a QuickMD doctor to see if estradiol vaginal inserts are the right option for you.
How to use
Use estradiol vaginal inserts only as directed by your QuickMD doctor. This medication is for vaginal use only and should not be taken by mouth. Wash your hands before and after inserting. Place the single use vaginal applicator into the vagina. Be sure to insert the full dose as prescribed. Staying on schedule helps keep hormone levels steady and symptoms under control. Each prescription comes with a patient information leaflet. Be sure to read it carefully, and ask your doctor if you have any questions.
Benefits
- Relief from vaginal dryness, burning, and itching
- Greater comfort during intimacy and sex
- Reduction in pain or irritation with urination
- May help prevent frequent urinary tract infections (UTIs)
- Restores moisture and elasticity to vaginal tissue
- Low-dose, localized treatment with minimal systemic absorption
- Bioidentical estrogen that matches your body’s own
- Small, easy-to-use insert for discreet, targeted relief
Side effects
Serious or adverse side effects from estradiol vaginal inserts are rare. However, some women may experience mild vaginal irritation, itching, discharge, or light spotting, especially when starting treatment. Less commonly, breast tenderness, nausea, or headaches may occur.
This is not a full list of side effects, interactions, or warnings, and it should not replace medical advice. For guidance tailored to your health and medications, always talk with your healthcare provider or pharmacist.
Safety information
Estradiol vaginal inserts must be prescribed by a licensed doctor. A consultation with a QuickMD doctor is required to review your health and determine if this prescription medication is appropriate for you.
Frequently asked questions
How much do estradiol vaginal inserts cost?
Estradiol vaginal inserts are $49 with QuickMD’s cash-pay option, giving you clear, upfront pricing with no hidden fees. Many women prefer this route because it’s simple, stress-free, and allows their medication to be shipped right to their door. If you’d rather use insurance, your doctor can send your prescription to your local pharmacy. Costs and coverage depend on your plan, but your QuickMD doctor will walk you through the options so you can choose what works best for your health, your budget, and your life.
How far to insert an estradiol applicator?
The estradiol applicator is typically inserted into the vagina as far as it will comfortably go, usually until the base of the applicator is at the vaginal opening. Once in place, the plunger is pressed to release the medication. Always follow the instructions provided with your prescription and use exactly as directed by your healthcare provider.
Do I need a prescription for estrogen suppositories?
Yes. Estradiol vaginal suppositories (inserts) are prescription medications. A licensed healthcare provider must evaluate your symptoms and determine if this treatment is appropriate for you.
How the membership works
Book your first visit. It’s free to start!
To begin your MHT Membership, book your first visit with a QuickMD doctor who understands perimenopause and menopause. Start with your first month free, then continue at $79 per month, which includes a doctor’s visit, your prescription, and ongoing care. During your first appointment, your doctor will review your health history, listen to your symptoms, and answer your questions. Together, you’ll decide whether hormone therapy feels right for you and start care that’s supportive, personal, and focused on lasting relief.
Unlock the perks of woman-centered care
Your membership gives you immediate access to answers when you need them most. Each month, your first doctor’s visit is included in your membership, and if you need additional support, extra visits are just $49. If medication could help ease your symptoms, your doctor will take the time to discuss your options and prescribe what you need during your visit. You can choose to have it shipped directly to your home with transparent pricing, or sent same-day to your local pharmacy. There are no contracts to lock you in, so you can cancel anytime. It’s flexible care built around what you’re going through, so you get the care you deserve.
Find relief with Estradiol vaginal inserts, if right for you
If your doctor determines estradiol vaginal inserts are right for you, they can prescribe them as part of your treatment plan. Each insert delivers a low dose of estrogen directly to the vaginal tissues, helping restore balance and relieve dryness, itching, and discomfort. With regular use, many women notice greater comfort during intimacy, less daily irritation, and improvements in urinary health. Over time, vaginal tissue can regain moisture and elasticity, making everyday life feel more comfortable. With your membership, you’re able to have check in with your doctor to track progress and adjust care as needed.
Get Estradiol vaginal inserts at QuickMD
Available 7 days a week
Same day appointments
Licensed & certified providers
Affordable, compassionate care
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