What you’ll learn
In this article, you’ll learn how to recognize the signs of hormone imbalances and what they may signal about your overall health. We’ll break down the role of important hormones like estrogen and testosterone, explain how hormone replacement therapy (HRT) can help, and highlight when to seek support from a licensed provider for more personalized care.
For your body to function its best, your hormone levels need to be in balance. This applies to men and women of all ages, not just those over the age of 50. While menopause typically occurs around that time, hormonal shifts and imbalances can start much earlier and affect your physical, mental, and emotional health.
The tricky part is that the signs of hormonal imbalance aren’t always obvious. Fatigue might be chalked up to a busy schedule. Mood swings can easily be mistaken for stress. But if you’re noticing persistent symptoms that are disrupting your daily life, it might be time to consider whether hormone replacement therapy (HRT) could help.
What is hormone replacement therapy (HRT)?
Hormone replacement therapy (HRT) is a treatment that replenishes hormones that the body no longer produces in sufficient amounts. HRT is often used in menopause therapy to treat symptoms of menopause by restoring optimum levels of estrogen and progesterone. HRT can help combat menopausal symptoms like hot flashes, night sweats, and vaginal dryness.
But HRT isn’t just for women going through menopause. It can also be beneficial if you’re experiencing early menopause, perimenopause, or have low testosterone. It may even help with thyroid-related imbalances or other hormone-related conditions like polycystic ovary syndrome (PCOS) or fibroids. Treatment can come in various forms, including pills, patches, creams, or injections. If you think HRT may be helpful, a conversation with a licensed provider can help you determine what’s right for you.
8 signs you might need hormone replacement therapy
Hormones act as chemical messengers, influencing everything from sleep and metabolism to mood, memory, and sex drive. When those hormones drop or fluctuate more than they should, you might notice changes in how you feel, think, and function.
So, what are the signs you might need hormone replacement therapy?
Hormonal imbalances can show up in different ways depending on which hormone is affected, so we’ve grouped the most common ones by the hormone typically responsible. Below are eight common signs that could indicate you’re dealing with a hormonal imbalance.
Low estrogen symptoms
Estrogen plays a key role in regulating reproductive health, mood, bone strength, skin elasticity, and body temperature. When estrogen levels begin to decline during perimenopause or menopause, you may start experiencing a range of symptoms.
These symptoms tend to show up gradually. You might feel “off” at first, but over time, the discomfort can grow.
1. Hot flashes
A hot flash is a sudden feeling of intense warmth, usually in the upper body, face, and chest. It often comes on without warning and may be accompanied by sweating, a flushed appearance, and even chills after the heat subsides. These symptoms can be very quick or last for hours. Hot flashes are caused by changes in how the brain regulates body temperature when estrogen levels drop.
2. Vaginal dryness
Estrogen helps maintain healthy vaginal tissue. When your estrogen levels dip, vaginal walls can become thin, dry, and less elastic. This can lead to itching, burning, pain during sex, and even an increased risk for urinary tract infections. These changes are part of a condition called vaginal atrophy, which is common after menopause.
3. Night sweats
Night sweats are hot flashes that happen while you sleep. You may wake up drenched in sweat with soaked pajamas and bedding, making it more difficult to fall back to sleep and disrupting a good night’s rest. Like daytime hot flashes, night sweats stem from the brain’s altered temperature control due to low estrogen. They can significantly impact sleep quality and daytime energy levels.
Low testosterone symptoms
Although it’s often labeled a “male hormone,” testosterone is important for women, too! In both women and men, testosterone supports energy levels, muscle mass, mental clarity, and sexual health. When these levels drop (especially during perimenopause), symptoms can show up in some subtle yet frustrating ways.
4. Fatigue
If you feel like your energy levels are dragging throughout the day, even after a full night’s sleep, it might be a sign of low testosterone. This hormone helps maintain steady energy levels and physical stamina. Without enough of it, your cells can struggle to convert nutrients into energy to help you get through your day. This can leave you tired and sluggish more often.
5. Low libido
Testosterone plays an important role in your sex drive (often called “libido”). This hormone enhances nerve sensitivity, lubrication, and blood flow to the genitals, making intimacy more comfortable and enjoyable. When testosterone levels drop, so does your libido. You might find yourself disinterested in sex or having difficulty getting aroused, which can affect your relationships and self-esteem.
6. Brain fog
Life is busy, so a little forgetfulness is normal. However, if you find yourself frequently struggling to focus or feeling mentally fuzzy, low testosterone might be the reason. Testosterone supports healthy brain function by helping protect nerve cells and promoting blood flow to the brain. Without it, you may feel like your thoughts are clouded or your brain is chugging along more slowly than usual.
Thyroid or other hormonal imbalances
Besides estrogen and testosterone, your body depends on multiple hormones to function properly. When thyroid hormones or other regulatory hormones are out of balance, symptoms can surface that overlap with other conditions.
7. Mood swings
If your mood shifts quickly from happy to anxious or irritable, you could be dealing with a hormone imbalance. Hormones influence neurotransmitters in your brain. Neurotransmitters are chemical messengers, like serotonin and dopamine, that help regulate emotions. When hormone levels change, these brain chemicals can become disrupted, leading to emotional instability.
8. Sleep disturbances
Difficulty falling or staying asleep may be more than just stress. Hormones like estrogen, progesterone, and melatonin help regulate your sleep cycles and body temperature. When they’re out of balance, your sleep cycle can be thrown off. You might find yourself waking frequently, sleeping lightly, or feeling less-than-refreshed in the morning.
Are these symptoms normal for your age?
Understanding what symptoms are normal for your age can help you take control of your health and make a decision that works for you. The following chart gives you a look at the symptoms you can expect during perimenopause and menopause.
Common signs you may need HRT by age:
| Are these symptoms common? | 30s | 40s – perminopause | 50s+ – menopause |
| Vaginal dryness | No | Yes | Yes |
| Hot flashes | No | Yes | Yes |
| Night sweats | No | Yes | Yes |
| Mood swings | No | Yes | Yes |
| Fatigue | No | Yes | Yes |
| Low libido | No | Yes | Yes |
| Brain fog | No | Yes | Yes |
| Sleep disturbances | No | Yes | Yes |
How HRT can help with different menopause symptoms
If several of these signs feel familiar, it may be time to speak with a licensed provider. Hormone replacement therapy can help relieve many of the symptoms caused by hormone fluctuations or deficiencies. Here’s how it works for different conditions:
| Symptoms | How HRT can help |
| Irregular periods | Irregular periods refer to periods that come sooner or later than expected. You may skip months and experience menstrual flow that is lighter or heavier than usual. HRT stabilizes estrogen and progesterone, which helps regulate your menstrual cycle and ease symptoms like heavy bleeding or missed periods. |
| Hot flashes | Hot flashes occur when estrogen levels drop because the hormone disrupts body temperature regulation. By supplementing these declining levels, HRT helps to stabilize temperature control. |
| Night sweats | Because estrogen helps to regulate your body’s temperature control system, lower levels of this hormone cause you to sweat profusely at night. HRT therapy restores estrogen levels, allowing your hypothalamus (the part of your brain that controls body temperature) to work more efficiently and reduce hot flash episodes. |
| Insomnia | Lower levels of both estrogen and progesterone cause disruptive symptoms of menopause, including hot flashes and night sweats. These symptoms can interfere with getting a good night’s sleep. By easing hot flashes and supporting melatonin production, HRT promotes more restful, uninterrupted sleep. |
| Depression and anxiety | HRT helps balance hormone levels that influence serotonin, a brain chemical linked to mood. If you’re feeling low, anxious, or emotionally out-of-sync, rebalancing your hormones may help improve stability. |
| Weight fluctuations | When estrogen, progesterone, and testosterone levels drop, so do your energy levels and overall metabolic rate. Low estrogen leads to more fat storage and lower muscle mass. HRT can make it easier to maintain a healthy weight and support muscle mass by improving metabolic efficiency. |
| Poor concentration & memory loss | Estrogen and testosterone are essential for brain health. Lower levels of these hormones can lead to brain fog and trouble remembering. Estrogen promotes nerve growth and brain cell communication, while testosterone strengthens blood flow. When hormone levels are stable, your memory and focus may sharpen. |
| Vaginal dryness | Low estrogen levels cause vaginal tissue to become thin and dry. This can make sex painful and increase the odds of developing a urinary tract infection (UTI). HRT restores moisture and elasticity to vaginal tissues, reducing discomfort and improving sexual health. |
| Heart palpitations | Estrogen helps regulate how blood vessels and the heart respond to stress and activity. When your levels drop, it can result in an irregular heart rhythm. HRT supports cardiovascular function by stabilizing blood pressure, reducing inflammation, and improving vessel elasticity. |
When to talk to a provider
Hormonal changes are a normal part of life, but that doesn’t mean you have to suffer through them without support. Now that you know the answer to the question, “What are the signs that you need HRT?”, you can take the next step. If you’re noticing symptoms that are interfering with your quality of life, it may be time to consider hormone therapy.
