Does Suboxone® change your personality?

June 29, 2025

9 minutes

Patient utilizing therapy to manage emotions

What you’ll learn

We’ll explain why some emotional changes are a regular part of early recovery on Suboxone®, not a side effect of the medication. You’ll also see what current research says about Suboxone®’s potential mood benefits, how to get support if things feel overwhelming, and why the effects of Suboxone® on mental health and personality are complex and vary from person to person.

Starting medication for opioid use disorder is a big step, and it’s totally natural to have questions. One of the most common is: “Will Suboxone® change my personality?”

Maybe you’ve heard that it makes people feel flat or emotionally numb. Maybe you’ve seen someone go through early recovery and seem totally different. Or maybe you’re just wondering what “normal” even looks like after opioid use.

Recovery brings emotional changes. But that doesn’t mean Suboxone® changes who you are. 

At QuickMD, we’ve helped thousands of people start and stick with treatment for opioid use disorder. Our licensed providers understand both the science behind Suboxone® and the emotional ups and downs of recovery, because we see it every day. 

Our approach is rooted in evidence-based care, empathy, and confidentiality, and we know how to walk with you through those early questions.

In this article, we’ll look at what’s really behind those shifts in mood or personality, why early recovery can feel strange at first, and how to get support if things feel overwhelming. We’ll also explore what the science says about Suboxone® and its role in treating opioid addiction, including its effects on the brain and early research suggesting it may actually improve mood for some people.

Let’s walk through the facts so you can make informed, confident choices in your recovery.

What people mean by “personality changes” on Suboxone®

When people talk about “Suboxone® personality changes,” they’re usually describing shifts in their mood, motivation, or how they react emotionally.

But here’s the important thing: while Suboxone® can affect your mood and emotions during the adjustment period, these changes are typically temporary and related to your brain’s healing process rather than permanent personality alterations. They’re usually part of your system finding its new balance.

So what’s really going on? The answer lies in understanding the recovery process.

In most cases, the changes people notice are part of the recovery process, not a direct effect of the medication. The effects of Suboxone® are more related to supporting a person’s mental health. That helps to stabilize mood and reduce withdrawal symptoms, rather than causing any personality changes.

Emotional side effects of Suboxone®

Some common side effects and experiences people report in early Suboxone® treatment include:

  • Mood swings or irritability
  • Feeling emotionally “numb”
  • Anxiety or restlessness
  • Trouble focusing or feeling motivated
  • Frustration or irritability

But these aren’t personality changes in the truest sense.

They’re usually symptoms of:

  • Post-acute withdrawal (also known as PAWS)
  • Mental health conditions that may have been masked by opioid use
  • Lifestyle shifts that come with stopping drug use (such as new routines, stressors, or relationships)
  • Unprocessed emotions resurfacing after long periods of suppression

So if you’re feeling “off,” it doesn’t mean Suboxone® is changing who you are. It means your brain and body are adjusting. That’s a natural, healthy part of the healing process.

As your system attunes, you’re getting one step closer to feeling more emotionally grounded. You’ll start to feel stronger, steadier, and more in control.

How Suboxone® for addiction treatment affects the brain and mood

Understanding what’s happening in your brain can help you feel more confident and in control as you move forward.

Suboxone® is a combination of two medications: buprenorphine and naloxone.

  • Buprenorphine is a partial opioid agonist. That means it attaches to the same opioid receptors in the brain that drugs like heroin, oxycodone, or fentanyl bind to, but it activates them much more gently. This helps reduce cravings and withdrawal symptoms without creating the high associated with full opioids.
  • Naloxone is included to prevent misuse. It blocks opioid receptors if the medication is injected improperly, but when taken as prescribed (sublingually, under the tongue), it has little to no effect.

So what does this have to do with mood?

When you stop using opioids, your brain needs time to rebuild the natural balance of its reward and motivation systems. It’s because of how opioids rewire your brain. Opioid use often suppresses your brain’s ability to make its own feel-good chemicals like dopamine and endorphins. 

During recovery, people can feel flat, low-energy, or emotionally raw. Not because Suboxone® is dulling their emotions, but because they’re no longer feeling numb from opioid use.

In fact, some early research suggests buprenorphine may actually have mild antidepressant properties. This was especially the case for people with both opioid use disorder and depression. In some small studies, even low doses helped reduce depressive symptoms quickly, sometimes within just a few days. 

Researchers believe this is partly due to its action on kappa opioid receptors, which are involved in mood and stress. For many, this translates to feeling more emotionally stable and more like themselves again once treatment begins.

Want more info on how Suboxone treatment works? Check out our QuickMD Learning Center to get more insight on opioid addiction treatment, advice, and tips.

Managing Suboxone® mood swings: how to feel more like yourself again after opioid use

Having mood swings and feeling off emotionally can be unsettling, especially when you’re trying to rebuild your life. But there are ways to support your mental health and start to feel like yourself again. Preventing relapse is a huge part of staying in recovery, and having solid support makes all the difference.

Whether that’s a structured treatment program, ongoing counseling, or other resources, that kind of foundation can really help you manage your emotions and keep moving forward.

1. Give your brain time to heal

Getting off opioids is a huge step, but your brain also needs time to catch up. Dopamine, sleep patterns, and stress levels all take a hit during addiction and need space to rebalance.

Your physical health might be improving, but your psychological symptoms can take more time to catch up. Many people start to notice small shifts week by week, as their brain chemistry gradually stabilizes.

2. Stay consistent with Suboxone®

Sticking to your Suboxone® treatment exactly as prescribed really helps keep those cravings in check and reduces your risk of relapse.

Suboxone® is a key piece of what’s called Medication-Assisted Treatment (MAT). MAT is a substance use treatment method that uses medication along with medical support to give you the best shot at recovery.

3. Get mental health support from therapy

Talking to a therapist can really help you sort through those intense emotions and learn better ways to handle stress. Therapy is also great for understanding and dealing with all the emotional ups and downs that can hit during recovery, things like mood swings, feeling depressed, or anxiety.

Cognitive behavioral therapy (CBT) and mindfulness-based approaches are especially helpful for managing mood swings in recovery.

Need someone to talk to?

Speak to one of our licensed counselors who understands both substance use and mental health. No waiting rooms. No judgment. Just real support, on your terms.

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4. Build structure into your day

Having a routine can make a huge difference. Routines help reduce stress and give your brain something predictable to focus on. Try to sleep at regular times, eat regularly, and set simple goals each day. 

These little anchors help steady your mood and energy.

5. Practice self-kindness

You don’t have to push through this alone. There’s help, medically, emotionally, and socially, to support you as you regain emotional stability.

Still don’t feel like yourself on Suboxone®? Why that’s normal in recovery

Even if you’re no longer in withdrawal and you’re taking Suboxone® as prescribed, the emotional ups and downs can stick around a little longer than expected. That can be a common phase in early recovery.

But here’s the thing: if you try to tough it out alone without support while quitting drugs, you could end up facing some setbacks or other problems that make recovery harder.

Emotional healing takes time

Suboxone® stabilizes your body, but emotional recovery often comes in waves. For many people, using opioids was a way to numb deep emotional pain. When that numbing stops, old feelings and unresolved issues may come to the surface, which can feel overwhelming or unfamiliar.

You may also be rebuilding parts of your life, relationships, routines, and purpose. Feeling off-balance during that process is normal.

It might not be the medication

Sometimes, it’s easy to point the finger at a medication like Suboxone® when something feels off. 

But in many cases, what’s really going on is:

  • Untreated mental health symptoms, like anxiety or depression.
  • Stress from life changes, like housing, work, or relationships.
  • Sleep issues or poor nutrition, both of which affect mood.
  • Loneliness or isolation, where emotional distress may increase.

Mental health symptoms, stress, or life transitions can also affect how you feel. A QuickMD provider can help you sort out what’s emotional vs. medication-related.

You’re recovering. And that process takes time, patience, and support.

How QuickMD supports opioid use disorder recovery on Suboxone®

We understand that starting or staying on Suboxone® treatment is a deeply personal decision. Our licensed providers offer judgment-free, affordable care from the privacy of your home. Whether you’re new to treatment or managing long-term recovery, we’re here to help you feel stable, supported, and heard.

The most effective treatment for opioid use disorder combines medications like Suboxone® with counseling and other support, because this whole process works best when you have people in your corner. Our treatment approach is designed to help you break free from opioid use and promote your well-being, building a solid foundation for lasting recovery.

We offer affordable, online access to licensed doctors specializing in addiction treatment. You don’t need to step into a clinic or share your story with anyone you’re not ready to. For many, this kind of privacy makes all the difference.

Many of our patients say they finally feel like themselves again with consistent care and medication that actually works.

One patient shared:

When I feared I might relapse, I turned to QuickMD. The care I received helped me stabilize, and for the first time in years, I feel like my best self again…with QuickMD, everything stays confidential.

QuickMD Patient

If you’re worried about cost, know that QuickMD operates on a self-pay model that many find simpler and more transparent than traditional healthcare. There are no surprise bills, and you can often get care the same day.

Suboxone® is just one part of recovery. Having compassionate, knowledgeable support behind it can make all the difference. And here’s something important to know: Suboxone® is generally safe to use long-term if that’s what you need to stay in recovery.

Ready for the next step?

Our licensed providers can explain how Suboxone® works, what you can expect in the first days of treatment, and how to tailor your addiction treatment plan with no judgment.

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Frequently asked questions about Suboxone® personality changes

Will Suboxone® make me feel “high” or disconnected from reality?

No. Suboxone® is designed to prevent the high that comes from full opioids. When taken as prescribed, it doesn’t produce euphoria or distort your thinking.

In fact, many people report feeling more mentally present and emotionally grounded compared to when they were actively using opioids or dealing with withdrawal.

Is it normal to feel anxious or moody after starting Suboxone®?

Yes, emotional ups and downs are common in the first few weeks to months.

These can genuinely make you feel like a different person as your brain adjusts to the medication and recovers from opioid use. While these changes can affect how you interact with others and handle daily situations, they’re typically part of your brain finding its new balance rather than permanent personality alterations.

If you’re feeling unusually anxious or low, talk to your QuickMD provider. Sometimes adjusting the dose or adding therapy can help ease your transition and manage opioid cravings.

How long does it take to emotionally stabilize on Suboxone®?

Everyone’s timeline is different. Some people start to feel balanced within days or weeks, while others might need a few months to fully settle into their new baseline. Emotional recovery takes longer than physical withdrawal. 

The more support you have from QuickMD providers, therapy, or the community, the smoother that process tends to be.

Disclaimer

Articles on this website are meant for educational purposes only and are not intended to replace professional medical advice, diagnosis or treatment. Do not delay care because of the content on this site. If you think you are experiencing a medical emergency, please call your doctor immediately or call 911 (if within the United States). This blog and its content are the intellectual property of QuickMD LLC and may not be copied or used without permission.

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