Published: June 5, 2024

Does Clonidine Work for Opioid Withdrawal? Understanding Its Benefits and Usage

Written by QuickMD Publications Team

2 minutes

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When treating opioid use disorder (OUD), clonidine can help alleviate some acute symptoms of withdrawal.

What Symptoms Does Clonidine Help Treat?

  • Hot flashes
  • Sweating
  • Muscle pain
  • Nasal discharge (runny nose)
  • Anxiety
  • Irritability

How Does Clonidine Work?

Unlike buprenorphine, clonidine is not an opioid agonist, meaning it does not attach to opioid receptors in the brain and spinal cord. Clonidine was initially developed to control high blood pressure. It releases norepinephrine from nerve cells naturally found in the nervous system. When a nerve cell releases norepinephrine, it is taken up by the next nerve in a chain, leading to muscle relaxation and lowered pain. For this reason, it is sometimes used alongside anesthetics to help with pain control.

Is Clonidine Used for Long-Term Treatment?

Unlike buprenorphine, clonidine is not used for long-term treatment of opioid use disorder. It is typically given in the early stage of treatment to lessen the discomfort of withdrawal before Suboxone is started or along with the first doses of Suboxone to help with any precipitated withdrawal symptoms.

How Much Does Clonidine Cost?

The price for 30 tablets of 0.1 mg clonidine starts at around $5. To see clonidine prices in your area and get a coupon, visit the GoodRx clonidine page.

Where Can I Get a Prescription for Clonidine?

The QuickMD providers are well-trained in treating patients with opioid use disorder and can prescribe medications like clonidine to help with the transition to Suboxone. Talk with a QuickMD provider to see if clonidine is a good solution for you.

Get Professional Advice on Clonidine with QuickMD

For personalized advice and support in managing opioid withdrawal, QuickMD’s telemedicine urgent care services are here to help. Consult with a QuickMD provider today to explore your options for managing withdrawal symptoms effectively.

Are you struggling with opioid withdrawal? Visit QuickMD today to schedule your telemedicine appointment and get expert guidance on managing withdrawal symptoms with clonidine and other treatments.

Disclaimer

Articles on this website are meant for educational purposes only and are not intended to replace professional medical advice, diagnosis or treatment. Do not delay care because of the content on this site. If you think you are experiencing a medical emergency, please call your doctor immediately or call 911 (if within the United States). This blog and its content are the intellectual property of QuickMD LLC and may not be copied or used without permission.

QuickMD has strict referencing policies and relies on reputable sources, including peer-reviewed research, clinical guidelines, medical organizations, and government and public health agencies, among others. Learn more about how we ensure accuracy in our content by reading our editorial guidelines.

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