Trazodone (Desyrel®)
Trazodone is a prescription antidepressant often used off-label as a sleep aid. It works by calming serotonin activity in the brain to reduce the nighttime tension and restlessness that make it hard to fall and stay asleep.
- Get care from a real doctor, without leaving home
- Same-day prescriptions available
- Medication delivered free, straight to your door
Book a visit to meet with a QuickMD doctor for a trazodone prescription or refill
A QuickMD doctor can prescribe medication only after your visit, and prescriptions aren't guaranteed. The listed price covers medication only and doesn't include the cost of your doctor visit.
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Get trazodone prescribed online from the comfort of home. $99 visit fee—no insurance required.
Getting started with trazodone at QuickMD
Description
Trazodone is FDA-approved for depression and is widely used off-label as a sleep aid. It works by adjusting serotonin activity in the brain to promote drowsiness and reduce the nighttime tension and worry that can make sleep difficult. When prescribed appropriately, many patients notice meaningful improvements in how quickly they fall asleep, how long they stay asleep, and how they feel the following day.
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Take trazodone by mouth with a glass of water, shortly after a meal or light snack, once a day, at the same time each day, or as directed by your QuickMD doctor. Taking it with food helps reduce the chance of dizziness or an upset stomach. If your doctor prescribes it for sleep, take it shortly before bedtime. Always use this medication exactly as prescribed by your doctor. Staying on schedule helps your body maintain consistent levels of the medication, which makes the treatment more effective. Each prescription comes with a patient information leaflet. Be sure to read it carefully, and ask your doctor if you have any questions.
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- Improved mood and a greater sense of emotional stability
- Reduced feelings of anxiety and tension
- Better sleep quality, including falling asleep faster and staying asleep longer
- Relief from symptoms of depression, such as persistent sadness and loss of interest
- Fewer sleep disturbances
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Serious or adverse side effects from trazodone are rare. However, some patients may experience:
- Drowsiness
- Dizziness
- Dry mouth
- Headache
- Blurred vision
- Nausea
- Fatigue
Contact your doctor right away if you experience signs of serotonin syndrome (a rare but serious reaction that can include rapid heart rate, confusion, and muscle twitching), irregular heartbeat, prolonged or painful erection (priapism), or worsening depression or suicidal thoughts.
This is not a full list of side effects, interactions, or warnings, and it should not replace medical advice. For guidance tailored to your health and medications, always talk with your healthcare provider or pharmacist.
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Trazodone must be prescribed by a licensed doctor. Like any medication, trazodone comes with important safety considerations, including possible side effects, serious risks, and certain conditions where it may not be safe to use. A consultation with a QuickMD doctor is required to review your health and determine if this prescription medication is appropriate for you.
Trazodone may not be appropriate if you:
- Are taking or have recently taken an MAO inhibitor (such as phenelzine or selegiline)
- Are taking linezolid or methylene blue
- Have a known allergy or hypersensitivity to trazodone
- Have a history of heart disease, irregular heartbeat, or QT prolongation
- Have a history of priapism or conditions that increase the risk of prolonged erection
- Have liver or kidney impairment, without close monitoring and dose adjustment
- Have a history of bipolar disorder or mania, without first discussing risks with your doctor
- Are pregnant, planning to become pregnant, or breastfeeding, without first discussing risks with your doctor
This is not a complete list of precautions, contraindications, or drug interactions. Always talk with your healthcare provider or pharmacist about your medical history and any medications or supplements you are taking before starting trazodone.
Trazodone
Start feeling better mentally and emotionally. Meet with a QuickMD doctor and, if appropriate, receive a prescription for trazodone. No insurance required.
- Support your mental health with proven treatment
- Same-day prescriptions available after your visit
- Delivered straight to your door when prescribed
Medication price does not include the cost of your doctors visit.
Frequently asked questions
Trazodone can help relieve symptoms of anxiety, particularly when anxiety occurs alongside depression or sleep difficulties. While it is not FDA-approved specifically for anxiety disorders, doctors commonly prescribe it off-label for this purpose. Its calming effect on the central nervous system can help reduce tension and promote a greater sense of calm. A QuickMD doctor can evaluate your symptoms and determine whether trazodone is the right fit for your treatment plan.
No, trazodone is not a controlled substance. Unlike many sleep aids, it is not classified as a controlled substance by the DEA, which means it does not carry the same dependence or misuse risk as medications in that category. It can be prescribed through a standard online visit with a QuickMD doctor, with no prior authorization required, and your prescription ships directly to your door through QuickMD Home Delivery.
Trazodone is not commonly associated with significant weight gain. Some patients may notice minor changes in appetite in the early weeks of treatment, but these effects tend to be modest. If you have any concerns about side effects while taking trazodone, your QuickMD doctor is available to monitor your progress and adjust your treatment plan if needed.
Start treatment with trazodone online
Book your first visit
Getting started begins with a simple online visit. You'll meet with a licensed QuickMD doctor from the comfort of home, where you can talk openly about what you've been going through and what kind of support you're looking for. The process is designed to feel comfortable, supportive, and pressure-free, so you can move forward with a clear understanding of what to expect and what comes next.
Learn more about trazodone
Your doctor will take time to understand any sleep difficulties you're facing, your health history, and what you've tried so far. If trazodone is appropriate, they'll guide you through how it works in your body, how to take it, what to expect, and how it can help you fall asleep faster and stay asleep longer. You'll leave your visit feeling informed and confident in your next steps.
Get your medication delivered
If your doctor prescribes trazodone, your prescription is sent directly to our pharmacy partner and shipped straight to your door. You'll receive clear instructions on how to take it, and your care doesn't stop there. Follow-up visits give your doctor a chance to check in on how you're responding, adjust your dose if needed, and make sure you're getting the support and relief you need.
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