Sertraline (Zoloft®)
Sertraline is a prescription antidepressant that works to address changes linked to low serotonin levels. It helps improve mood, reduce anxiety, ease panic attacks, restore motivation, and support overall emotional well-being.
- Get care from a real doctor, without leaving home
- Same-day prescriptions available
- Medication delivered free, straight to your door
Book a visit to meet with a QuickMD doctor for a sertraline prescription or refill
A QuickMD doctor can prescribe medication only after your visit, and prescriptions aren't guaranteed. The listed price covers medication only and doesn't include the cost of your doctor visit.
You deserve to feel good every day
Get sertraline prescribed online from the comfort of home. $99 visit fee—no insurance required.
Getting started with sertraline at QuickMD
Description
Sertraline is FDA-approved for depression and anxiety, including generalized anxiety disorder (GAD), social anxiety, panic disorder, and PTSD (post-traumatic stress disorder). It works by increasing serotonin levels in the brain to help stabilize mood, reduce feelings of fear and worry, and restore your interest in daily life. When prescribed appropriately, many patients also notice improvements in sleep, energy, and their ability to engage with the people and activities that matter most to them.
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Take sertraline by mouth with a glass of water, once a day, at the same time each day, or as directed by your QuickMD doctor. You may take it with or without food. If you experience stomach upset, take it with food to help reduce nausea. Always use this medication exactly as prescribed by your doctor. Staying on schedule helps your body maintain consistent levels of the medication, which makes the treatment more effective. Each prescription comes with a patient information leaflet. Be sure to read it carefully, and ask your doctor if you have any questions.
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- Improved mood and a greater sense of emotional stability
- Reduced feelings of anxiety and fear
- Fewer and less intense panic attacks
- Restored interest and motivation in daily activities
- Better sleep quality and increased energy levels
- Long-term effectiveness
- Well-established safety record
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Serious or adverse side effects from sertraline are rare. However, some patients may experience:
- Nausea
- Dry mouth
- Increased sweating
- Trouble sleeping
- Mild tremors (shakiness)
- Changes in weight
- Reduced sex drive
- Restlessness
Contact your doctor right away if you experience signs of serotonin syndrome (a rare but serious reaction that can include rapid heart rate, confusion, and muscle twitching), unusual bleeding, or worsening depression.
This is not a full list of side effects, interactions, or warnings, and it should not replace medical advice. For guidance tailored to your health and medications, always talk with your healthcare provider or pharmacist.
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Sertraline must be prescribed by a licensed doctor. Like any medication, sertraline comes with important safety considerations, including possible side effects, serious risks, and certain conditions where it may not be safe to use. A consultation with a QuickMD doctor is required to review your health and determine if this prescription medication is appropriate for you.
Sertraline may not be appropriate if you:
- Are taking or have recently taken an MAO inhibitor (such as phenelzine, selegiline, or linezolid)
- Are taking pimozide
- Have a known allergy or hypersensitivity to sertraline
- Are taking disulfiram (applies to the oral concentrate form only)
- Are in the first trimester of pregnancy or breastfeeding, without first discussing risks with your doctor
This is not a complete list of precautions, contraindications, or drug interactions. Always talk with your healthcare provider or pharmacist about your medical history and any medications or supplements you are taking before starting sertraline.
Sertraline
Start feeling better mentally and emotionally. Meet with a QuickMD doctor and, if appropriate, receive a prescription for sertraline. No insurance required.
- Support your mental health with proven treatment
- Same-day prescriptions available after your visit
- Delivered straight to your door when prescribed
Medication price does not include the cost of your doctors visit.
Frequently asked questions
Sertraline tablets are $41 with QuickMD’s cash-pay option, giving you clear, upfront pricing with no hidden fees. Prescriptions are filled through QuickMD Home Delivery and shipped right to your door.
Most patients begin to notice early improvements particularly in sleep, energy, and appetite within the first one to two weeks. The full antidepressant and anti-anxiety effects typically take four to six weeks to develop. It’s important to keep taking sertraline as prescribed during this period, even if you don’t feel a difference right away. You will follow up with QuickMD doctor to track your progress and adjust your dose if needed.
Avoid alcohol while taking sertraline, as it can increase the risk of side effects like dizziness and drowsiness. Do not take sertraline with MAOIs (monoamine oxidase inhibitors—a separate class of antidepressants that includes medications like Nardil and Parnate). Use caution with NSAIDs like ibuprofen and aspirin, as these can raise your bleeding risk. Always let your doctor know about any other medications, vitamins, or supplements you’re taking before beginning treatment.
Start treatment with sertraline online
Book your first visit
Getting started begins with a simple online visit. You'll meet with a licensed QuickMD doctor from the comfort of home, where you can talk openly about what you've been going through and what kind of support you're looking for. The process is designed to feel comfortable, supportive, and pressure-free, so you can move forward with a clear understanding of what to expect and what comes next.
Learn more about sertraline
Your doctor will take time to understand any challenges you're facing, your mental health history, and what you've tried so far. If sertraline is appropriate, they'll guide you through how it works in your body, how to take it, what to expect, and how it can help you stabilize your mood, reduce anxiety, and restore your interest in daily life. You'll leave your visit feeling informed and confident in your next steps.
Get your medication delivered
If your doctor prescribes sertraline, your prescription is sent directly to our pharmacy partner and shipped straight to your door. You'll receive clear instructions on how to take it, and your care doesn't stop there. Follow-up visits give your doctor a chance to check in on how you're responding, adjust your dose if needed, and make sure you're getting the support and relief you need.
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