Published: June 5, 2024

Switching from Methadone to Suboxone: How Long Do I Need to Wait?

Written by QuickMD Publications Team

2 minutes

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Methadone has been a longstanding treatment for opioid use disorder (OUD). However, it is slowly becoming less popular and is being replaced by buprenorphine (Suboxone). Because of the danger of overdose, methadone has to be administered in person at a methadone clinic (i.e., direct observed therapy, or DOT) generally at least six days a week. Suboxone, in contrast, can safely be taken at home without any significant risk of a fatal overdose.

This has led many people to transition from methadone to Suboxone. The most important consideration when switching over to Suboxone is the waiting period before taking the first dose of buprenorphine (Suboxone).

How Long Should Patients Wait After Finishing Methadone to Start Suboxone?

Because methadone takes a long time to leave the system, it is best to wait at least 72 hours (3 days) before starting Suboxone.

This is to avoid the signs and symptoms of precipitated withdrawal. These may include:

  • Muscle pain
  • Cramps
  • Diarrhea
  • Fever
  • Sweating
  • Dilated pupils
  • Insomnia
  • Depression
  • Suicidal thoughts
  • Rapid heartbeat
  • High blood pressure
  • Pain, including headaches
  • Anxiety
  • Nausea and vomiting
  • Runny nose
  • Goosebumps
  • Chills

What if Waiting 3 Days is Too Difficult?

If waiting three days is too difficult, micro-dosing can be an option: Suboxone can be given in smaller-than-usual doses at frequent intervals to avoid withdrawal symptoms. Doses as small as 0.5 mg are taken (instead of the usual 8 mg). However, the longer a person can wait, the smoother the transition will be.

How Can I Switch to Suboxone from Methadone?

QuickMD is the largest teleMOUD provider in the United States. We can prescribe Suboxone to you via telemedicine and guide you through the transition. QuickMD providers can also prescribe adjunct medications to help you with any withdrawal symptoms you may experience during the transition period.

Conclusion

Switching from methadone to Suboxone can significantly improve your quality of life by allowing you to take your medication at home. You can make a smooth and safe transition by understanding the waiting period and the importance of avoiding precipitated withdrawal.

Ready to make the switch? Contact QuickMD today to speak with a provider who can guide you through the process and ensure you have the support you need during your transition from methadone to Suboxone.

Disclaimer

Articles on this website are meant for educational purposes only and are not intended to replace professional medical advice, diagnosis or treatment. Do not delay care because of the content on this site. If you think you are experiencing a medical emergency, please call your doctor immediately or call 911 (if within the United States). This blog and its content are the intellectual property of QuickMD LLC and may not be copied or used without permission.

QuickMD has strict referencing policies and relies on reputable sources, including peer-reviewed research, clinical guidelines, medical organizations, and government and public health agencies, among others. Learn more about how we ensure accuracy in our content by reading our editorial guidelines.

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