Estradiol + norethindrone
Estradiol + norethindrone tablets (generic Activella) are a prescription medication that combine two hormones your body naturally produces. They help restore hormone balance, ease hot flashes, sleep disturbances, and mood changes, and support vaginal and bone health.
- Talk directly with a doctor about your symptoms
- Same-day prescriptions available
- 100% online with fast, free delivery
Book a visit and get estradiol + norethindrone as soon as today
*A QuickMD doctor can prescribe medication only after your visit, and prescriptions aren't guaranteed. The listed price covers medication only and doesn't include the cost of your doctor visit.
You deserve to feel like yourself again
Get estradiol + norethindrone prescribed online today by doctors who understand women's health. Doctor visits are just $79—no insurance required.
Estradiol + norethindrone now available at QuickMD
Description
Estradiol + norethindrone tablets are a combination of estrogen and progestin commonly prescribed to help manage perimenopause and menopause, offering both symptom relief and hormone support. They may also be used for women whose bodies do not make enough of these hormones on their own. Together, they help restore hormone balance, improve mood swings, sleep, brain fog, and vaginal dryness, ease symptoms like hot flashes and night sweats, and support vaginal and bone health. The addition of progesterone (norethindrone) also helps protect the uterus from abnormal tissue growth. When prescribed appropriately, they provide balanced hormone support for women.
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Take estradiol and norethindrone tablets exactly as directed by your QuickMD doctor. Swallow one tablet by mouth each day with a glass of water, at the same time each day. You may take it with or without food. Do not take more often than directed. Taking your medication consistently helps keep hormone levels steady and care effective. Each prescription comes with a patient information leaflet. Be sure to read it carefully, and ask your doctor if you have any questions.
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- Reduces the risk of endometrial hyperplasia
- Supports bone strength and long-term skeletal health
- Protects the uterus with added progesterone
- Helps ease hot flashes and night sweats during menopause
- May improve mood stability and reduce irritability
- Supports vaginal comfort and reduces dryness
- Promotes better sleep quality and nighttime rest
- Simple, once-daily tablet
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Serious or adverse side effects from estradiol and norethindrone tablets are rare. However, some women may experience:
- Nausea
- Breast tenderness
- Bloating
- Headaches
- Spotting or light bleeding (particularly in the first few months)
- Fluid retention
- Mood changes
- Weight fluctuations
- Melasma
This is not a full list of side effects, interactions, or warnings, and it should not replace medical advice. For guidance tailored to your health and medications, always talk with your healthcare provider or pharmacist.
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Estradiol and norethindrone must be prescribed by a licensed doctor. A consultation with a QuickMD doctor is required to review your health and determine if this prescription medication is appropriate for you.
Common brand name(s): Abigale, Abigale Lo, Activella, Amabelz, Lopreeza, Mimvey, Mimvey Lo
Contraindications:
- Unexplained vaginal bleeding
- Known or suspected breast cancer or estrogen-dependent cancer
- Active or history of blood clots (DVT, PE)
- Active or recent arterial thromboembolic disease (stroke, heart attack)
- Liver dysfunction or disease
- Known hypersensitivity to estradiol, norethindrone, or any ingredients in the formulation
- Pregnancy
- Uncontrolled high blood pressure
- Migraine with aura
- Smoking in women over age 35
This is not a complete list of precautions, contraindications, or drug interactions. Always talk with your healthcare provider or pharmacist about your medical history and any medications or supplements you are taking before starting estradiol and norethindrone.
Estradiol + norethindrone
Start feeling better today. Meet with a QuickMD doctor and, if appropriate, receive an estradiol prescription to help you feel your best. No insurance required.
- Relieve menopausal symptoms with hormone therapy
- Prescription provided after your visit, often the same day
- Fast shipping to your doorstep when prescribed
Medication price does not include the cost of your doctors visit.
Frequently asked questions
Some women notice small changes in weight or fluid retention when starting estradiol and norethindrone, while others do not. These shifts are usually mild and may improve as your body adjusts. If you’re concerned about weight changes, your QuickMD doctor can talk through what’s normal, what to watch for, and ways to support your overall well-being while taking estradiol and norethindrone.
Estradiol and norethindrone tablets are $44 with QuickMD’s cash-pay option, giving you clear, upfront pricing with no hidden fees. Prescriptions are filled through QuickMD Home Delivery and shipped right to your door.
Estradiol is a form of estrogen, the hormone that helps relieve menopause symptoms like hot flashes, night sweats, and vaginal dryness. Norethindrone is a form of progesterone, which balances estrogen and protects the lining of the uterus. Together, they work as a team to ease symptoms while helping keep your uterus healthy.
Getting prescribed estradiol + norethindrone online
Book your first visit
Talk to a QuickMD doctor by video or phone for just $79, at a time that works for you. Your doctor will take time to truly understand your health history, listen to what you're experiencing, and answer every question you have. Because when you feel confident about your care, that's when real progress happens. Appointments are available same-day, so you can get started quickly.
Learn more about estradiol + norethindrone
Your doctor will walk you through how estradiol and norethindrone work together and the specific benefits this combination can provide. You'll discuss the proper dosing and talk through any possible side effects so you know exactly what to expect. Together, you'll decide if this combination is the right fit for you.
Get quick relief with estradiol + norethindrone
If estradiol + norethindrone are right for you, your doctor will prescribe them as part of your care. Your medication is then fulfilled through QuickMD Home Delivery at our low cash-pay pricing of just $44 for a 30-day supply, shipped straight to your door so you can get started right away. No waiting at the pharmacy or making extra trips.
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